Bioinformatics Scientist - Algorithm & Assay Development

Inivata Great Abington United Kingdom Computational Biology

Company Description

We are a leader in liquid biopsy. Every day we transform the lives of cancer patients and their families through the power of liquid biopsy.  Our tests unlock essential genomic information from a simple blood test and allow clinicians to make more informed treatment decisions for their patients.

We are dynamic and innovative, focused on the development of new ground-breaking technologies in a fast-paced and international setting. Our exceptional team of talented and driven individuals work together to combine their energy and expertise in world-class research, product development and commercialization to bring new tests to the patients that need them.

If making a difference is in your DNA and you are ready to join the liquid biopsy revolution, then you could be just the person we are looking for to join our team based in Cambridge, UK!

Position

The R&D Computational Biology group are looking to recruit a highly motivated bioinformatician to develop the next generation of analysis methods to detect and monitor ctDNA. This role will interact closely with the assay development team on design of new products and improvement of existing assays. This position offers the exciting opportunity to work at the frontier of cancer diagnostics while participating in the entire product development pipeline from concept, clinical validation, to commercial product launch.

This role will involve the analysis of NGS cancer genomics data, biomarker development, innovative algorithm design and optimisation of Inivata’s technology. We expect that applicants will have prior experience in the field of bioinformatics and a good understanding of NGS analysis with an MSc or PhD degree in a relevant field and/or industry experience.

There is flexibility for the exact profile and experience of the applicant, provided that they can demonstrate qualities in the general area of computational biology and motivation to join a rapidly growing company in the field of cancer genomics.   

Key Responsibilities:

  • Contribute to the development of novel methodologies and algorithms for the analysis of ctDNA.
  • Analyze, summarize and interpret NGS data sets using existing and customized approaches.
  • Device new analytical solution in the context of assay development and clinical data analysis.
  • Develop production ready, regulatory compliant code in partnership with the software development team.
  • Support the rollout, optimisation and improve scalability of Inivata’s analysis pipelines.

Requirements

Education/Qualifications:

  • PhD in the field of computational biology/bioinformatics, or significant experience in that space.

Requirements:

  • Experience with analytical development, pipeline creation and custom analysis for next generation sequencing data (Essential).
  • Scientific programming experience, using either R or Python (Essential).
  • Experience with Unix environment, high-performance computing and common bioinformatics tools and resources (Essential).
  • Experience in novel algorithm development or data mining (Essential).
  • Excellent communication and presentation skills and propensity to work in a multi-disciplinary environment (Essential).
  • Experience in designing and implementing tests (i.e. unit or system tests) and in testing frameworks (e.g., circleCI) for the development of production ready software (Desired).
  • Prior development experience in a regulatory environment, familiarity with software management (version control), design control procedures and quality assurance, such as ISO 13485, EN 62304, ISO 15189 or FDA/MolDX/CAP accreditation (Desired).
  • Experience with processing exome and/or whole genome datasets preferably within a cancer genomics context (Desired).
  • Demonstrated experience with the creation of software tools, software packages/modules or published Bioinformatics scripts/pipelines (Desired).

Other information

Location:

Inivata Limited is based in Cambridge, UK. 

No agencies please.

The closing date for applications is: 8th July 2020

To Apply: https://cezanneondemand.intervieweb.it/inivata/jobs/bioinformatics_scientist__algorithm__assay_development_9567/en/

Our TRANSFORM Values guide all our activities:

Team, Results, Ambitious, Nimble, Solutions, Focused, Openness, Recognize, Make a difference

 

 

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