Heptares Therapeutics is an established UK biotech company with world-class technology in structure-based drug design applied to discovery of novel small molecules acting through GPCRs.

The company is developing its own pipeline of proprietary molecules and works in collaboration with major global pharmaceutical companies on both small molecule and antibody discovery programmes. The most advanced of these are now in clinical studies with others moving towards clinical development.

The company is currently based in Welwyn Garden City but will be moving to a brand-new research facility at Granta Park (Cambridge) in August 2018. Heptares has been operating for over ten years and has approximately 130 employees who will all be based in this new research facility. The size of the company ensures a transparent linkage between all activities from early discovery through to clinical development.

Heptares is currently looking to strengthen and expand its capabilities in the immunology/inflammation therapeutic areas. As a result, we now seek to recruit a highly motivated laboratory-based in vitro pharmacologist to join our Molecular Pharmacology team. The Molecular Pharmacology team is responsible for both new drug target validation and supporting all drug discovery phases up to pre-clinical candidate (PCC) selection including assay development, provision of routine small/large molecule screening and more detailed mechanism of action studies.

Ideally, candidates should have experience in the field of immunology, as demonstrated through a post-doctoral academic / industry background and prior experience of GPCRs. The candidate must have a thorough knowledge of experimental design, and a high level of technical laboratory skill. Preferable techniques include, cell culture/immune cell isolation, GPCR signaling, qPCR technology platforms, flow cytometry and assay automation techniques.

Candidates should possess a PhD/postgraduate degree in immunology, pharmacology, biochemistry or similar biological sciences. Candidates must be highly motivated, flexible scientists with the ability to multi-task. Good interpersonal skills are also essential as you will be working closely with other members of key drug discovery programmes and with scientists from other disciplines in support of our research projects.

Applicants must be able to demonstrate proof of the right to work in the United Kingdom.

Heptares is an equal opportunities employer.

Applications should include a covering letter, providing a short description of the background to their interest in the role, with curriculum vitae including the names and contact details for two referees. Please send your application in pdf format quoting reference number 2018/1MP. The closing date for applications is 21st June 2018.

Strictly, no agencies.