Sosei Heptares is an international biopharmaceutical company with a mission to make a significant contribution to improving the quality of life and health of people around the world. To achieve this, we will discover, design, and develop the most innovative and effective medicines for patients worldwide, through our world-leading patent-protected technology and platform.

Our core focus is on the discovery and early development of new medicines originating from our proprietary G Protein-Coupled Receptor (GPCR) targeted StaR® technology and Structure Based Drug Design (SBDD) platform capabilities. Today, we are advancing a broad and deep pipeline of novel medicines across multiple therapeutic areas, including neurology, immunology, gastroenterology, and inflammation diseases.

We have established partnerships with some of the world’s leading pharmaceutical companies and multiple emerging technology companies, including AbbVie, AstraZeneca, Biohaven, Genentech (Roche), GSK, Neurocrine Biosciences, Novartis, Pfizer, Takeda and Verily.

Sosei Heptares is headquartered in Tokyo, Japan with corporate and R&D facilities in London and Cambridge, UK. We have approximately 170 employees based at our state-of-the-art R&D research centre at Granta Park, Cambridge. The size of our company ensures optimum agility and transparent linkage between all activities from early discovery through to clinical development.

For more information, please visit https://soseiheptares.com/. LinkedIn: @soseiheptaresco | Twitter: @soseiheptaresco | YouTube: @soseiheptaresco

We are currently looking to strengthen our Molecular Pharmacology team and are now seeking to recruit a highly motivated and experienced Principal Scientist, to join our team. The Molecular Pharmacology team is responsible for supporting targets from Target Validation through to Candidate Nomination.

Main tasks will include:

• Project management
• Developing robust in vitro assays to support Hit ID
• Routine screening, data upload and QC of results in internal databases
• Working with primary cell assays to help establish Target Engagement and Biomarkers assays to support compound progression
• Mentoring others (may have direct line management responsibilities)
• Initiation and management of studies at Contract Research Organisations
• Regular communication and interaction with external research partners
• Technical and strategic input into area of expertise

• Extensive experience working within a collaborative, multi-disciplinary, pharmaceutical/biotech environment with a track record of scientific achievements and contributions.
• Proven project management experience (effective project management skills)
• Therapeutic expertise within the areas of immunology or neuroscience
• Ability to work flexibly within a team, whilst being highly self-motivated and able to work independently
• Analytical thinking and good problem-solving skills
• Excellent organisational and time-management skills, as well as the ability to work to strict deadlines
• The ability to communicate clearly, both verbally and in written reports, in English.

Desirable but not essential includes:

• Previous experience with GPCRs
• Previous line management responsibilities.

What’s in it for you?

• State-of-the-art R&D centre located in the heart of the Cambridge science cluster
• Competitive compensation package including discretionary cash bonuses
• Eligible for grants of Restricted Stock Units in Sosei Group Corporation
• 25 days annual leave in addition to public holidays
• Employer contribution to pension
• Private Medical Insurance and a cash plan for dental and optical reimbursement
• Health and wellbeing benefits including a subsidised individual gym membership
• Income protection to cover long term absences due to ill health
• Group Death in Service equal to 4x basic annual salary

Why Sosei Heptares?

At Sosei Heptares, we are dedicated to the pursuit of scientific innovation. Our mission is to make a significant contribution to improving the quality of life and health of people around the world. To achieve this, we will discover, design, and develop the most innovative and effective medicines for patients worldwide, through our world-leading patent-protected technology and platform

Working at Sosei Heptares

The Sosei Heptares R&D centre is a modern, state-of-the-art centre located within easy shuttle reach of Cambridge and Whittlesford Parkway train stations. We offer a collaborative, diverse and inclusive working environment that considers your individual needs and believes in maintaining a sustainable work-life balance. You will be welcomed by a team of colleagues with decades of accumulated experience in their areas of expertise, happy to help you develop your own skills in a highly collaborative environment and who are keen to provide guidance and support in your personal and career development plans.

Our Vision and Values

To become one of Japan’s science and technology-led biopharmaceutical drug discovery champions. To achieve this, we will leverage our global know-how and operating agility to deliver a sustainable pipeline of first or best-in-class therapeutics, ensuring our place amongst the next generation of leading innovators.

We are guided by three fundamental values.

• Limitless Compassion
• Unswerving passion
• Continuous self-innovation

These unchanging set of core values that serves as a guide across all our activities

Join Us!

The successful candidate will be employed by Heptares Therapeutics Ltd, a UK wholly owned subsidiary of Sosei Group Corporation.

Sosei Heptares is committed to building a diverse and ambitious workforce, and to promoting equal opportunities in employment. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment: we do not discriminate based on age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation, or any other classification prescribed by law

Applications should include a covering letter, providing a short description of the background to their interest in the role, with curriculum vitae including the names and contact details for two referees. Please apply through our on-line job’s portal with your application in pdf format, quoting reference number 2021-PS-MP. The closing date for applications is 31st March 2022.

Sosei Heptares does not accept speculative or unsolicited CVs from agencies. All speculative or unsolicited CVs submitted without an agreement in place will be considered Sosei Heptares property and will not obligate us to pay a referral fee.

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